Unlockable characters
| Unlockable | How to Unlock |
| Unlock Boogey | In Mission Mode Finish Mission 9 in "Tier 4" |
| Unlock Chicken | Finish Story Mode with all characters on any difficulty with 10 hours of gameplay |
| Unlock Dracula | In Mission Mode finish Mission 5 in "Tier 3" |
| Unlock Eris | Finish "Story Mode" once with either Billy, Mandy, Grim, Or Irwin |
| Unlock Fred Fredburger | Finish "Story Mode" once with either Billy, Mandy, Grim, Or Irwin |
| Unlock General Skarr | In Mission Mode finish Mission 6 in "Tier 4" |
| Unlock Hoss Delgado | Finish Mission 9 in Tier 1 in "Mission Mode" |
| Unlock Jack O'Lantern | In Mission Mode finish Mission 9 in "Tier 2" |
| Unlock Lord Pain | Finish Mission 9 in Tier 5 |
| Unlock Mogar | Finish "Story Mode" once with either Billy, Mandy, Grim, Or Irwin |
| Unlock Nergal | Finish "Story Mode" once with either Billy, Mandy, Grim, Or Irwin |
| Unlock Nergal Jr. | In Mission Mode finish Mission 9 in "Tier 3" |
| Unlock Nerglings | Finish Story Mode with all characters on any difficulty |
| Unlock Vikings | Finish Story Mode with all characters and destroy every letter in the credits sequence |